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Common genetic variation has an important role in the etiology of schizophrenia, and larger studies will allow more detailed understanding of this disorder.
Genome-wide association studies (GWASs) have been successful at identifying single-nucleotide polymorphisms (SNPs) highly associated with common traits...
Chromosome 6q26-27 is linked to susceptibility to visceral leishmaniasis (VL) in Brazil and Sudan.
Genotyping has become more cost-effective and less invasive with the use of buccal cell...
Barrett's esophagus is an increasingly common disease that is strongly associated with reflux of stomach acid and usually a hiatus hernia,...
Leishmania braziliensis causes cutaneous (CL) and mucosal (ML) leishmaniasis. In the mouse, Fli1 was identified as a gene influencing enhanced wound healing...
To understand how HLA-DR contributes to disease pathogenesis, we examined expression at the protein level in circulating myeloid and lymphoid cells of VL patients
We confirmed the strong association between high DAT and/or rK39 titers and progression to disease among asymptomatic subjects
Overall the analyses do not suggest individual sequence variants account for differences in clinical outcome or adaptation to different hosts.
These results highlight how UNICORN can enable reliable, powerful, and convenient genetic association analyses without access to the individual-level data