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Preparing for Life: Plasma Proteome Changes and Immune System Development During the First Week of Human LifeNeonates have heightened susceptibility to infections. The biological mechanisms are incompletely understood but thought to be related to age-specific adaptations in immunity due to resource constraints during immune system development and growth. We present here an extended analysis of our proteomics study of peripheral blood-plasma from a study of healthy full-term newborns delivered vaginally, collected at the day of birth and on day of life (DOL) 1, 3, or 7, to cover the first week of life. The plasma proteome was characterized by LC-MS using our established 96-well plate format plasma proteomics platform.
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Children with chronic suppurative lung disease have a reduced capacity to synthesize interferon-gamma in vitro in response to non-typeable Haemophilus influenzaeThe aim of this study was to identify features of innate, cell-mediated and humoral immunity that may increase susceptibility to respiratory infections in...
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Update of the WHO/IUIS Allergen Nomenclature Database based on analysis of allergen sequencesThis paper summarizes updates of allergen names approved at the meetings of the IUIS Allergen Nomenclature Sub-Committee in 2011 through 2013.
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Immune Responses to Allergens in Atopic Disease: Considerations for BioinformaticsAllergies are mediated by several immunological mechanisms that make different contributions in different patients.
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The cat lipocalin Fel d 7 and its cross-reactivity with the dog lipocalin Can f 1Fel d 7 is a common allergen in a Swedish cat-sensitized population that cross-reacts with Can f 1
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A longitudinal study of natural antibody development to pneumococcal surface protein A families 1 and 2 in Papua New Guinean Highland children: a cohort studyPneumococcal surface protein A is immunogenic and natural anti-PspA immune responses are acquired through exposure and develop with age
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Effect of amino acid polymorphisms of house dust mite Der p 2 variants on allergic sensitizationMeasures of allergic sensitization and therapeutic strategies could be optimized with knowledge of Der p 2 variants
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Analysis of IgE binding patterns to house dust mite allergens in scabies-endemic communities: insights for both diseasesThis study analysed the IgE binding patterns caused by house dust mite allergens in scabies endemic communities in Australia.
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Hypersensitivity: ImmunologicalThis comprehensive review provides an introduction to immunological hypersensitivity, discusses the sensitisation of T-cell lineages.
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Lower anti-echovirus antibody responses in children presenting to hospital with asthma exacerbations.This article assesses the absolute and specific antibody titres to VP1 antigens of the gut-trophic enteroviruses, echovirus 30 and Sabin 1 poliovirus, in...