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Researchers urge caution in how asthma test is usedResearchers are urging caution in the use of a widely accepted test for diagnosing asthma, after their study found it may not be accurate in some settings.
Research
Targeting the mucosal immune system in a pregnant mouse model to prevent experimental allergic airways disease in the offspringStudies in Europe show exposure of pregnant women to high levels of microbial products stimulate immune function maturation in their offspring
Research
The cellular effects of estrogen on allergic asthmaThe study aims to identify the mechanism for this so that this knowledge can be used to better treat asthma and allergies in both males and females.
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Mechanisms of IgE sensitizationThis project investigates how cells of the immune system respond to substances to cause allergies to help develop new treatments.
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Airway Epithelial Cell Immunity Is Delayed During Rhinovirus Infection in Asthma and COPDWe propose that propensity for viral exacerbations of asthma and COPD relate to delayed expression of epithelial cell innate anti-viral immune genes
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Pulmonary microRNA profiles identify involvement of Creb1 and Sec14l3 in bronchial epithelial changes in allergic asthmaIn this study, we aimed to use microRNAs-which are critical regulators of signaling cascades-to identify so far uncharacterized asthma pathogenesis pathways
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Association between human rhinovirus C and severity of acute asthma in childrenA new and potentially more pathogenic group of human rhinovirus (HRV), group C (HRVC), has recently been discovered.
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Immune modulation by UV: Role of vitamin DIn this chapter, evidence for and evidence against the involvement of vitamin D in the immunoregulatory properties of UV radiation is presented.
Research
Reversible Control by Vitamin D of Granulocytes and Bacteria in the Lungs of Mice: An Ovalbumin-Induced Model of Allergic Airway DiseaseVitamin D may be essential for restricting the development and severity of allergic diseases and asthma, but a direct causal link between vitamin D...
Research
Two newly identified cat allergens: The von Ebner gland protein Fel d 7 and the latherin-like protein Fel d 8Characterization of the complete IgE binding spectrum of cat allergens is important for the development of improved diagnosis and effective immunotherapeutics.