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Research

Longitudinal study of language and speech of twins at 4 and 6 years: Twinning effects decrease, zygosity effects disappear, and heritability increases

This study investigates the heritability of language, speech, and nonverbal cognitive development of twins at 4 and 6 years of age.

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Pre-onset risk characteristics for mania among young people at clinical high risk for psychosis

We aimed to identify the rate and predictors of transition to mania in a cohort of youth with clinical or familial risk for psychosis.

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Initial acquisition and succession of the cystic fibrosis lung microbiome is associated with disease progression in infants and preschool children

We characterized the lower airways microbiome using BAL samples obtained from clinically stable CF young children who underwent bronchoscopy and chest CT.

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Persistent activation of interlinked type 2 airway epithelial gene networks in sputum-derived cells from aeroallergen-sensitized symptomatic asthmatics

Our findings provide new insight into the molecular mechanisms operative at baseline in the airway mucosa in atopic asthmatic with natural aeroallergen exposure

Research

Does the reason matter? How student-reported reasons for school absence contribute to differences in achievement outcomes among 14–15 year olds

We used data from the Longitudinal Study of Australian Children to examine the reasons for 14-15 year old absences and how they relate to outcomes in year 9.

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The case for DNA methylation based molecular profiling to improve diagnostic accuracy for central nervous system embryonal tumors (not otherwise specified) in adults

We report the case of a 45-year-old woman who was diagnosed with a NOS based on immunohistochemical analysis of the patient's tumor at diagnosis.

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Do carer’s levels of unmet needs change over time when caring for patients diagnosed with high-grade glioma and how are these needs correlated with distress?

The aim of the current study was to determine how carer needs changed longitudinally and understand associations between unmet needs and distress.

Research

Cerebral palsy after assisted reproductive technology: a cohort study

To calculate the birth prevalence of CP after ART and compare the clinical outcomes of children with CP after ART or natural conception.

Research

The clinical utility of lung clearance index in early cystic fibrosis lung disease is not impacted by the number of multiple-breath washout trials

This study aimed to determine if relationships between LCI and clinical outcomes of CF lung disease differ when only two acceptable MBW trials are assessed.