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Hypomethylation of the CTGF gene locus is a common feature of paediatric pre-B acute lymphoblastic leukaemiaWe identified consistent hypomethylation of the CTGF locus in primary pre-B ALL specimens regardless of CTGF expression.
Research
Chest computed tomography: a validated surrogate endpoint of cystic fibrosis lung disease?Clinical trials for the treatment of cystic fibrosis (CF) lung disease are important to test and optimise new therapeutic interventions.
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DSM-IV-TR and DSM-5 eating disorders in adolescents: Prevalence, stability, and psychosocial correlates in a population-based sampleEating disorder prevalence rates were significantly greater when using DSM-5 than DSM- IV-TR criteria, at all time points for females and at age 17 only...
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Excessive daytime sleepiness increases the risk of motor vehicle crash in obstructive sleep apneaOur objectives were to describe the incidence rate of motor vehicle crashes (MVCs) in patients with obstructive sleep apnea (OSA) and to investigate MVC risk...
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Assessment and management of nutrition and growth in rett syndromeWe developed recommendations for the clinical management of poor growth and weight gain in Rett syndrome through evidence review and the consensus of an...
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A three generation study of the mental health relationships between grandparents, parents and childrenIt is well known that children of parents with mental illness are at greater risk of mental illness themselves.
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“I have a good life”: the meaning of well-being from the perspective of young adults with Down syndromeThe purposes of this study were to explore what makes for a "good life" from the perspective of young adults with Down syndrome and to identify the barriers...
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The Forms of Bullying Scale (FBS): Validity and Reliability Estimates for a Measure of Bullying Victimization and Perpetration in AdolescenceThe study of bullying behavior and its consequences for young people depends on valid and reliable measurement of bullying victimization and perpetration.
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Recommendations from a consensus development workshop on the diagnosis of fetal alcohol spectrum disorders in Australia.Fetal alcohol spectrum disorders (FASD) are underdiagnosed in Australia, and health professionals have endorsed the need for national guidelines for diagnosis.
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Promoting abstinence from alcohol during pregnancy: Implications from formative researchThis research developed messages to promote abstinence from alcohol during pregnancy and identified elements that enhance message persuasiveness.