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Genetic Variants in the IL-4/IL-13 Pathway Influence Measles Vaccine Responses and Vaccine Failure in Children from MozambiqueWe investigated IL-4, IL-13, and IL-4Rα polymorphisms and their impact on measles IgG responses and measles vaccine failure, in two separate cohort.
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Plasma C4d as marker for lupus nephritis in systemic lupus erythematosusIn the present study, we sought to evaluate the complement activation product C4d as a marker for lupus nephritis in systemic lupus erythematosus (SLE).
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Critical role of plasmacytoid dendritic cells in regulating gene expression and innate immune responses to human rhinovirus-16Though HRVs are usually innocuous viruses, they can trigger serious consequences in certain individuals, especially in the setting of IFN synthesis.
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REACH: study protocol of a randomised trial of rehabilitation very early in congenital hemiplegiaCongenital hemiplegia is the most common form of cerebral palsy (CP). Children with unilateral CP show signs of upper limb asymmetry by 8 months corrected age (ca) but are frequently not referred to therapy until after 12 months ca. This study compares the efficacy of infant-friendly modified constraint-induced movement therapy (Baby mCIMT) to infant friendly bimanual therapy (Baby BIM) on upper limb, cognitive and neuroplasticity outcomes in a multisite randomised comparison trial.
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How ‘healthy’ do children really need to be? Going beyond the limitsThe authors assessed the impact of including preschool‐aged children with a history of preterm birth, early life wheeze, asthma diagnoses and/or recent respiratory symptoms in healthy reference ranges for respiratory impedance using the forced oscillation technique (FOT).
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The Diverse Risk Profiles of Persistently Absent Primary Students: Implications for Attendance Policies in AustraliaUnderstanding variations in risk profiles among persistently non-attending children will inform the development of absence interventions.
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Validation of intellectual disability coding through hospital morbidity records using an intellectual disability population-based database in Western AustraliaTo investigate how well intellectual disability (ID) can be ascertained using hospital morbidity data compared with a population-based data source.
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Attenuated psychophysiological reactivity following single-session group imagery rescripting versus verbal restructuring in social anxiety disorderThe current study highlights the specificity of brief imagery-based interventions in influencing psychophysiological reactivity in social anxiety disorder
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After asthma: Redefining airways diseasesIdentify entrenched areas of asthma management and treatment in which progress has stalled and to challenge current principles
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Do carer’s levels of unmet needs change over time when caring for patients diagnosed with high-grade glioma and how are these needs correlated with distress?The aim of the current study was to determine how carer needs changed longitudinally and understand associations between unmet needs and distress.