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In an Australian-first, The Kids Research Institute Australia researchers have developed a new tool that could improve outcomes for children with a highly aggressive type of brain cancer.
Older maternal age is associated with depression, anxiety, and stress symptoms in young adult females
The current study examined the relationship between students’ mental and emotional wellbeing and factors pertaining to school climate, focusing on the...
This study aimed to identify psychosocial predictors in cystic fibrosis that may inform intervention strategies.
This paper explores the social and emotional wellbeing and mental health complexities for Western Australian adolescents when they transition to boarding school
When three-year-old Flo Parker injured her hip on a camping trip five years ago, her parents thought it would be nothing more than a common childhood injury.
This fact sheet addresses what we currently know about suicide prevention for Aboriginal and Torres Strait Islander peoples.
This factsheet highlights the need for a greater understanding of the importance of constructive & preventive ‘upstream’ approaches & sustained investment in...
While the majority of Aboriginal and Torres Strait Islander children are travelling on track or exceeding across all developmental domains...
In 2009 over 40 leading researchers and academics from across Australia signed the Boatshed Racism Roundtable Declaration that proposed four areas of action...
The Robert Connor Dawes Foundation has joined forces with the Ethan Davies Fellowship to co-fund a The Kids Research Institute Australia initiative aimed at uncovering new treatments for aggressive childhood brain tumours.
The current study investigated whether being exposed to maladaptive parenting (high hostility and low warmth) and/or marital conflict in infancy is...
Cancers in children are very different from cancers in adults - in most cases they appear to strike simply at random. They also develop differently and can spread more rapidly and aggressively. And because cancers in children are not obviously linked to their lifestyles, much work is needed to pinpoint their cause.
In the eating disorder sample but not the control sample, omega-3 and omega-6 fatty acid correlated significantly and negatively with eating disorder...
Pediatric patients with recurrent and refractory cancers are in most need for new treatments. This study developed patient-derived-xenograft (PDX) models within the European MAPPYACTS cancer precision medicine trial.
Invasive pulmonary aspergillosis remains a major cause of morbidity and mortality for immunocompromised children, particularly for patients with acute leukaemia and those undergoing haematopoietic stem cell transplantation. Timely diagnosis, using a combination of computed tomography (CT) imaging and microbiological testing, is key to improve prognosis, yet there are inherent challenges in this process. For CT imaging, changes in children are generally less specific than those reported in adults and recent data are limited.
Optic pathway gliomas (OPGs) are associated with significant risk of visual and endocrine morbidity, but data on long-term outcomes in symptomatic patients is sparse. This study reviews the clinical course, disease progression, survival outcomes and long-term sequelae in pediatric patients with symptomatic OPGs in our institution over three decades.
Diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPG), are the most lethal of childhood cancers. Palliative radiotherapy is the only established treatment, with median patient survival of 9 to 11 months. ONC201 is a DRD2 antagonist and ClpP agonist that has shown preclinical and emerging clinical efficacy in DMG.