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Research

Influenza is the most common vaccine-preventable disease in Australia, causing significant morbidity and mortality. We assessed the burden of influenza across all ages in terms of influenza-associated mortality and hospitalizations using national mortality, hospital-discharge and influenza surveillance data.

Research

Invasive fungal disease (IFD) is a common and important complication in children with acute myeloid leukaemia (AML). We describe the epidemiology of IFD in a large multicentre cohort of children with AML.

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Rapid blood culture pathogen identification facilitated by matrix-assisted laser desorption ionisation time-of-flight and GeneXpert has the potential to improve antibiotic prescribing. This study investigates the impact of these rapid diagnostics on the timeliness of effective and optimal antibiotic prescribing in paediatric patients with bacteraemia.

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Invasive group A streptococcal infection in Australian children is frequently severe and has a high long-term morbidity burden

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Palivizumab appeared effective for reducing virologically confirmed respiratory syncytial virus in this high-risk cohort

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Substantial spatial clustering of notified tuberculosis was detected at region, zone and district level in Ethiopia

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Childhood vaccination has played a critical role in the reduction of morbidity and mortality from communicable diseases, including specific respiratory pathogens

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Reliance on hospital discharge diagnosis codes alone will likely underestimate the burden of respiratory viruses

Research

Children with acute respiratory tract infection (ARTI) frequently exhibit virus-virus codetection, yet the clinical significance of ARTI remains contentious.