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Secondary care could be the optimal sector for managing child and adolescent obesity, given low primary care uptake and limited tertiary services.
Determining if hyperglycaemia prior to and during exercise affects the amount of carbohydrate required to maintain stable glucose levels during/after exercise
This study will evaluate the effect of two types of aerobic exercise
A Closed-Loop System will potentially have a major impact upon acute and chronic complications of diabetes as well as upon their quality of life.
Investigating changes in retinopathy, aortic intima media thickness & heart rate variability, indicators of macrovascular disease & autonomic neuropathy
To conduct an analysis of children with TIDM’s cognitive profile at an age in which both cognition and cortical development are still maturing
The purpose of this randomized clinical trial is to determine whether the use of the BIB aids weight loss in obese adolescents.
A register which stores demographic and clinical data on all patients attending the diabetes clinic at Princess Margaret Hospital
We conducted a methylome-wide association study to examine associations between DNA methylation in whole blood and central adiposity and body fat distribution, measured as waist circumference, waist-to-hip ratio and waist-to-height ratio adjusted for body mass index, in 2684 African-American adults in the Atherosclerosis Risk in Communities study.
Fetal exposure to maternal smoking during pregnancy is associated with the development of noncommunicable diseases in the offspring. Maternal smoking may induce such long-term effects through persistent changes in the DNA methylome, which therefore hold the potential to be used as a biomarker of this early life exposure. With declining costs for measuring DNA methylation, we aimed to develop a DNA methylation score that can be used on adolescent DNA methylation data and thereby generate a score for in utero cigarette smoke exposure.