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Delayed development of antibodies to S. pneumoniae in infancy is associated with the development of atopy and asthma.
Young adulthood is a critical life period for health and health behaviours.
There is substantial interest in studying lung function in infants, to better understand the early life origins of chronic lung diseases such as asthma.
This article assesses the absolute and specific antibody titres to VP1 antigens of the gut-trophic enteroviruses, echovirus 30 and Sabin 1 poliovirus, in...
This study analysed the IgE binding patterns caused by house dust mite allergens in scabies endemic communities in Australia.
High risk for virus-induced asthma exacerbations in children is associated with an IRF7lo immunophenotype, but the underlying mechanisms are unclear. Here, we applied a Systems Biology approach to an animal model comprising rat strains manifesting high versus low susceptibility to experimental asthma, induced by virus/allergen coexposure, to elucidate the mechanism(s)-of-action of the high-risk asthma immunophenotype.
Pat Deborah Holt Strickland PhD, DSc, FRCPath, FRCPI, FAA PhD Emeritus Honorary Researcher Head, Pregnancy and Early Life Immunology Patrick.Holt@
Epidemiologic associations between viral lower respiratory infections (LRIs) and asthma in later childhood are well known
Elucidation of early life factors is critical to understand the development of allergic diseases, especially those manifesting in early life such as food allerg
To determine whether changes in 24-hour average background ozone (O₃), nitrogen dioxide (NO₂), carbon monoxide (CO) and particulates < 10 μm (PM₁₀) increase the