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Research

X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes

Systematic sequencing of all X-chromosomal genes in patients with genetic evidence for X-chromosome locus involvement may resolve 58% of Fragile X-negative cases

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International research utilizing the Early Development Instrument (EDI) as a measure of early child development: Introduction to the Special Issue

This opening paper presents the background to this Special Issue devoted to new international research using Early Development Instrument

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Human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine for the prevention of cervical cancer and HPV-related diseases

HPV-16/18 AS04-adjuvanted vaccine reduces HPV-16/18 infection and associated cervical endpoints in women regardless of age, location, or sexual experience

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Undiagnosed Diseases Network International (UDNI): White paper for global actions to meet patient needs

This white paper discusses the global progress in understanding novel diseases with the aim of encouraging more collaboration between international...

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Neighbourhood characteristics and the rate of identification of young people at ultra-high risk for psychosis

This study aimed to determine if the rate of identification of young people at ultra-high risk for psychosis was associated with the level of social deprivation

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The prevention, diagnosis and management of central venous line infections in children

With advancing paediatric healthcare, the use of central venous lines has become a fundamental part of management of neonates and children.

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A prospective ultrasound study of prenatal growth in infant siblings of children with autism

Numerous studies have observed that a proportion of infants later diagnosed with autism spectrum disorder (ASD) experience accelerated head growth...

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Optimization is required when using linked hospital and laboratory data to investigate respiratory infections

Despite a recommendation for microbiological testing, only 45% of children hospitalized for respiratory infections in our previous data linkage study linked...

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Birthweight and childhood cancer: Preliminary findings from the international childhood cancer cohort consortium (I4C)

Background Evidence relating childhood cancer to high birthweight is derived primarily from registry and case-control studies.

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Addressing the relationship between racism and inequality in suicide...

In 2009 over 40 leading researchers and academics from across Australia signed the Boatshed Racism Roundtable Declaration that proposed four areas of action...