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Sexually dimorphic facial features vary according to level of autistic-like traits in the general populationThe current data provide support for Bejerot et al.'s androgyny account since males and females with high levels of autistic-like traits generally showed...
Research
Genome-wide association study of autistic-like traits in a general population study of young adultsResearch has proposed that autistic-like traits in the general population lie on a continuum, with clinical ASD representing the extreme end of this...
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Few sex differences in regional gray matter volume growth trajectories across early childhoodSex-specific developmental differences in brain structure have been documented in older children and adolescents, with females generally showing smaller overall brain volumes and earlier peak ages than males. However, sex differences in gray matter structural development in early childhood are less studied. We characterized sex-specific trajectories of gray matter volume development in children aged 2–8 years.
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Harmonization of SDQ and ASEBA Phenotypes: Measurement Variance Across CohortsHarmonizing the scores obtained by different instruments that measure the same construct enable researchers to combine them in one analysis. An important step in harmonization is checking whether there is measurement invariance across populations.
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Autism Early Intervention Providers: Their Priorities, Use of Empirically Supported Practices, and Professional Development NeedsAutism early intervention research has indicated a research-to-practice gap, including continued use of practices with inadequate research support, and insufficient use of empirically supported practices. The present study explored the processes and mechanisms through which providers working with young children on the autism spectrum learn, select, and implement the various practices in their clinical repertoires.
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Parsing the heterogeneity of social motivation in autismSocial motivation is posited as a key factor in the expression of the autism phenotype. However, lack of precision in both conceptualization and measurement has impeded a thorough understanding of its diverse presentation and associated outcomes. This study addresses this gap by identifying subgroups of autism characterized by deficits in distinct facets of social motivation, relative to normative benchmarks.
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A GWAS for grip strength in cohorts of children-Advantages of analysing young participants for this traitGrip strength is a proxy measure for muscular strength and a predictor for bone fracture risk among other diseases. Previous genome-wide association studies have been conducted in large cohorts of adults focusing on scores collected for the dominant hand, therefore increasing the likelihood of confounding effects by environmental factors.
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Commentary: A spectrum for all? A response to Green et al. (2023), neurodiversity, autism and health careThe broadening of the clinical definition of autism over time-the so-called, autism spectrum-has run in parallel with the growth of a neurodiversity movement that has reframed the concept of autism entirely. Without a coherent and evidence-based framework through which both of these advances can be situated, the field is at risk of losing definition altogether.
Research
Interactions between the lipidome and genetic and environmental factors in autismAutism omics research has historically been reductionist and diagnosis centric, with little attention paid to common co-occurring conditions (for example, sleep and feeding disorders) and the complex interplay between molecular profiles and neurodevelopment, genetics, environmental factors and health. Here we explored the plasma lipidome in 765 children (485 diagnosed with autism spectrum disorder (ASD)) within the Australian Autism Biobank.