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Landmark research investigating benefits of COVID-19 vaccination for kids set to launch at The Kids Research Institute AustraliaA first-of-its-kind national study looking at the optimal COVID-19 vaccination strategies for children and adolescents is set to begin at Perth’s The Kids Research Institute Australia thanks to a $3.8 million funding injection from the Australian Government’s Medical Research Future Fund (MRFF).

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Bacterial slime causing persistent wet coughs for childrenResearchers using powerful microscopes have identified bacterial slime in the lungs of some children with persistent wet coughs.

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The Kids researchers honoured at Premier’s Science AwardsCongratulations to Telethon Kids Institute researcher Dr Chris Brennan-Jones who was named Woodside Early Career Scientist of the Year at last night’s 2020 Premier’s Science Awards.

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Major grant awarded to tackle antibiotic resistanceVital research aiming to improve the treatment of potentially deadly Group A Streptococcus (Strep A) has been awarded $820,000 in the latest round of National Health and Medicine Research Council’s Ideas Grants.
Research
Pediatric Burn Survivors Have Long-Term Immune Dysfunction With Diminished Vaccine ResponseEpidemiological studies have demonstrated that survivors of acute burn trauma are at long-term increased risk of developing a range of morbidities. The mechanisms underlying this increased risk remain unknown. This study aimed to determine whether burn injury leads to sustained immune dysfunction that may underpin long-term morbidity. Plasma and peripheral blood mononuclear cells were collected from 36 pediatric burn survivors >3 years after a non-severe burn injury (<10% total body surface area) and from age/sex-matched non-injured controls.

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$2 million grant to develop diagnostic tool for rheumatic feverThe Kids Research Institute Australia & Menzies School of Health Research will lead an international project to develop a diagnostic tool for acute rheumatic fever.

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Implants could replace painful injections to treat rheumatic heart diseasePainful monthly penicillin injections to treat and prevent Rheumatic Heart Disease (RHD) could be replaced with a longer-acting implant, a recent study has found.

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Driving a vaccine revolutionThe Kids Research Institute Australia is now part of an ambitious, yet achievable, global bid to produce such one-shot vaccines.

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The Kids researchers granted $5 million to prevent RHD across PacificA team led by Dr Joseph Kado from the Wesfarmers Centre of Vaccines and Infectious Diseases, based at The Kids Research Institute Australia, and The University of Western Australia (UWA) has been awarded $5 million by the Federal Government in a major push to prevent rheumatic heart disease across the Pacific.
Research
The epidemiology of superficial Streptococcal A (impetigo and pharyngitis) infections in Australia: A systematic reviewStreptoccocal A (Strep A, GAS) infections in Australia are responsible for significant morbidity and mortality through both invasive (iGAS) and post-streptococcal (postGAS) diseases as well as preceding superficial (sGAS) skin and throat infection. The burden of iGAS and postGAS are addressed in some jurisdictions by mandatory notification systems; in contrast, the burden of preceding sGAS has no reporting structure, and is less well defined.