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Whole-of-Life Inclusion in Bayesian Adaptive Platform Clinical TrialsThere is a recognized unmet need for clinical trials to provide evidence-informed care for infants, children and adolescents. This Special Communication outlines the capacity of 3 distinct trial design strategies, sequential, parallel, and a unified adult-pediatric bayesian adaptive design, to incorporate children into clinical trials and transform this current state of evidence inequity. A unified adult-pediatric whole-of-life clinical trial is demonstrated through the Staphylococcus aureus Network Adaptive Platform (SNAP) trial.
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A Retrospective case-series of children with bone and joint infection from northern AustraliaWe report osteomyelitis incidence in indigenous children of northern Australia is amongst the highest reported in the world
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Comparison of three methods for the recovery of skin pathogens from impetigo swabs collected in a remote community of Northern Territory, AustraliaImmediate plating of impetigo swabs is the gold standard for bacterial recovery but is rarely feasible in remote regions.
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Ngangk Ngabala Ngoonda (Sun Safety)The ‘Ngangk Ngabala Ngoonda (Sun Safety) of Aboriginal young mob of WA’ is a community-led project that aims to identify the sun safety needs and strengthen sun safety knowledge of Aboriginal Children and Young People in Western Australia.
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Australian Group on Antimicrobial Research surveillance outcome programs - bloodstream infections and antimicrobial resistance patterns from patients less than 18 years of ageFrom 1 January 2020 to 31 December 2021, thirty-eight institutions across Australia submitted data to the Australian Group on Antimicrobial Resistance (AGAR) from patients aged < 18 years (AGAR-Kids). Over the two years, 1,679 isolates were reported from 1,611 patients. This AGAR-Kids report aims to describe the population of children and adolescents with bacteraemia reported to AGAR and the proportion of resistant isolates.
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Dedicated paediatric Outpatient Parenteral Antimicrobial Therapy medical support: a pre-post observational studyWe examined the impact of introducing a dedicated team to OPAT, to define the role of increased medical oversight in improving patient outcomes in this cohort.
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Evaluation of Pediatric HIV Postexposure Prophylaxis Guideline Following Child Sexual Assault in Western AustraliaHIV postexposure prophylaxis (PEP) following child sexual assault (CSA) is recommended in select cases. High rates of poor adherence to PEP are reported. We evaluated adherence to the recommended management of children following CSA at the tertiary pediatric facility in Western Australia and compared our approach with international guidelines.
News & Events
The Kids researchers named as finalists in 2023 Premier’s Science AwardsFive The Kids Research Institute Australia researchers working across diverse and highly impactful areas of child health research have been named as finalists for the 2023 Premier’s Science Awards.
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See, Treat, Prevent Skin Sores and Scabies (SToP) TrialHealthy skin is important for maintaining overall health and wellbeing. Some skin infections, if untreated, can lead to serious downstream health complications such as heart disease, kidney disease, or sepsis.
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Optimisation of sampling for a new Skin Microbiome assayAsha Janessa Tim Bowen Pickering Barnett BA MBBS DCH FRACP PhD GAICD FAHMS OAM BSc PhD PhD Head, Healthy Skin and ARF Prevention Senior Research