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We identified the existence of more than 290 clinically associated genomic phylogroups across 22 countries, highlighting challenges in designing vaccines of global utility
Indigenous patients are substantially underrepresented in care by services participating in the nationwide specialist palliative care Collaboration, likely reflecting widespread access barriers.
Systematic review of the treatment, prevention and public health control of skin infections in resource-limited settings where skin infections are endemic
Streptococcus pneumoniae causes substantial morbidity and mortality among children. The introduction of pneumococcal conjugate vaccines (PCV) has the potential to dramatically reduce disease burden. As with any vaccine, it is important to evaluate PCV impact, to help guide decision-making and resource-allocation.
We outline a series of research initiatives to improve identification of RHD in administrative data thereby contributing to monitoring the RHD burden globally
In the warmer tropical regions of WA no seasonality was observed, but overall incidence of LLC presentations were higher
Prevention strategies in ARF endemic settings may be enhanced by targeting new members entering a community and children in environments of close contact
We propose that hydroxychloroquine could be repurposed to reduce the risk of rheumatic heart disease after acute rheumatic fever
We analysed the stimulation of J8 antibodies in response to infection, and the role of existing J8 antibodies in protection against subsequent infection
The authors present a variety of pressing clinical research questions on optimal RHD prevention and advanced care