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Prenatal stress and risk of behavioral morbidity from age 2 to 14 years:The maternal experience of stressful events during pregnancy has been associated with a number of adverse consequences for behavioral development offspring...
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Low-moderate prenatal alcohol exposure and risk to child behavioural development: a prospective cohort studyTo examine the association of fetal alcohol exposure during pregnancy with child and adolescent behavioural development.
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Assessing the protective effect of influenza vaccine against laboratory confirmed influenza in hospitalised children aged 6-59 monthsInfluenza vaccine was offered to all children aged 6-59 months resident in Western Australia in 2008, and we wished to evaluate the effectiveness of this immunisation programme.
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Linking MECP2 and pain sensitivity: the example of Rett syndromeThis study investigated the nature and prevalence of atypical pain responses in Rett syndrome and their relationships with specific MECP2 mutations.
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Representativeness of child controls recruited by random digit diallingRecruiting control subjects who are representative of the population from which the cases are drawn is a challenge in case-control studies
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Dietary patterns and markers for the metabolic syndrome in Australian adolescentsOverweight and other risk factors for cardiovascular disease (CVD) as well as their clustering, are increasingly prevalent among adolescents.
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Association of pre-pregnancy weight and birth defectsAssociation of pre-pregnancy weight, birth defects
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The long-term effects of breastfeeding on child and adolescent mental health: A Pregnancy Cohort Study followed for 14 yearsTo determine whether there was an independent effect of breastfeeding on child and adolescent mental health
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Association between socioeconomic status and the development of asthma: analyses of income trajectoriesUsing data on 2868 children born in the Western Australian Pregnancy Cohort (Raine) Study, we examined the association between changes in family...
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Zika Virus Changes Methylation of Genes Involved in Immune Response and Neural Development in Brazilian Babies Born With Congenital MicrocephalyThe recent increase in babies born with brain and eye malformations in Brazil is associated with Zika virus (ZIKV) infection in utero. ZIKV alters host DNA methylation in vitro. Using genome-wide DNA methylation profiling we compared 18 babies born with congenital ZIKV microcephaly with 20 controls. We found ZIKV-associated alteration of host methylation patterns, notably at RABGAP1L which is important in brain development, at viral host immunity genes MX1 and ISG15, and in an epigenetic module containing the causal microcephaly gene MCPH1. Our data support the hypothesis that clinical signs of congenital ZIKV are associated with changes in DNA methylation.